Interleukin 4 - Wikipedia
The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (T h 0 cells) to T h 2 cells. Upon activation by IL-4, T h 2 cells subsequently produce additional IL-4 in …
Regulation of inflammation by interleukin-4: a review of …
In this review, recent advances in understanding these three IL-4-related branch points—alternative splicing of IL-4, differential receptor engagement by IL-4, and differential …
Interleukin 4 - an overview | ScienceDirect Topics
Interleukin-4 is a cytokine that is produced by various cells and plays a role in exerting anti-inflammatory effects during infections like tuberculosis. AI generated definition based on: …
Recent advances in understanding the role of IL-4 signaling
2021年9月7日 · Interleukin-4 (IL-4) is a four-α-helical bundle type I cytokine with broad pleiotropic actions on multiple lineages. Major actions of IL-4 were initially discovered for B and T cells, …
Interleukin - StatPearls - NCBI Bookshelf - National Center for ...
2022年8月22日 · Interleukin-4 (IL-4) CD4+T cells (Th2) synthesize IL-4, and it acts on both B and T cells. It is a B-cell growth factor and causes IgE and IgG1 isotype selection. It causes Th2 …
Tuning the Cytokine Responses: An Update on Interleukin (IL)-4 …
Interleukin (IL)-4 and IL-13 are related cytokines that regulate many aspects of allergic inflammation. They play important roles in regulating the responses of lymphocytes, myeloid …
IL-4 in the Brain: A Cytokine To Remember
2012年11月1日 · CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells.
Interleukin-4 as a therapeutic target - ScienceDirect
2023年2月1日 · Interleukin-4 (IL-4) is a pleiotropic cytokine mainly known for its role in type 2 immunity. Therapies antagonizing or blocking IL-4 activity have been developed to counteract …
Interleukins in cancer: from biology to therapy - Nature
2021年6月3日 · This Review provides an update of interleukins in tumour biology, covering the milestones of the latest discoveries of interleukin-related mechanisms in cancer, together with …
Regulation of IL4 gene expression by T cells and therapeutic ...
2003年7月1日 · Interleukin-4 (IL-4) is a key cytokine that controls the differentiation of T helper (T H) cells to the T H 2 effector cells that are responsible for cellular immunity and inflammation.