In vitro anti-cancer efficacy and phyto-chemical screening of …
网页2020年7月19日 · The high in-vitro anti-cancer activities of solvent extracts of Kigelia africana justify its use in traditional medicine to manage breast cancer. Phytochemical analysis of the extracts reveal similar profiles hence the differences in their anti-cancer activities can be attributed to quantitative variations of various classes of secondary ...
Gene expression and anticancer evaluation of Kigelia africana
网页2024年6月5日 · In this study, we aimed to assess the cytotoxic activity of Kigelia Africana (KA) extracts on breast cancer (MDA-MB-231 and MCF-7) and noncancerous kidney cells (HEK-293T) to develop an efficient anticancer medication.
Kigelia africana inhibits proliferation and induces cell death in …
网页2022年10月1日 · Kigelia africana (KA) is a medicinal plant with anti-cancer effects. KA has selective cytotoxic effects on high-risk neuroblastoma cells. KA inhibits proliferation and induces cell death in neuroblastoma cells. KA modulates protein expression and signaling pathways in neuroblastoma cells.
A survey of ethnomedicinal plants used to treat cancer by …
网页2020年9月14日 · For example, Kigelia africana (Lam.) Benth., highlighted by some practitioners in this study’ has been found from other studies to be useful for skin ailments (eczema, psoriasis, fungal infection, boils), diarrhoea, haemorrhoids, fever, malaria, diabetes as well as having anti-cancer properties .
Ethnobotany, Phytochemistry and Pharmacological Activity of Kigelia …
网页2020年6月15日 · Kigelia africana has also found application in traditional cancer therapy, and some studies support its cytotoxic effects on melanoma, Ehrlich ascites carcinoma and breast cancer
Ethnomedicinal Uses, Phytochemistry, and Anticancer Potentials of ...
网页2023年8月8日 · In several African countries, the fruit extracts of K. africana have been used traditionally as herbal remedies for the treatment of cancer-related infections, melanoma, skin neoplasms, and endometrial cancer [235,239].
Therapeutic importance of Kigelia africana subsp. africana
网页2023年11月3日 · These bioactive extracts of the plant possess anti-inflammatory, antioxidant, antimicrobial, antidiabetic, antineoplastic, and anti-urolithic activities. Due to its anti-inflammatory, antioxidant, and immune-booster properties, Kigelia can prove to be an essential source of drugs for treating various disorders.
Kigelia africana inhibits proliferation and induces cell death in …
网页Kigelia africana (KA) is a plant used in traditional African medicine which has already shown its anti-cancer potential in several in vitro and in vivo studies. The aim of this study is to evaluate the effect of KA fruit extract on stage 4 high-risk NB cells.
网页2024年6月5日 · In this study, we aimed to assess the cytotoxic activity of Kigelia Africana (KA) extracts on breast cancer (MDA-MB-231 and MCF-7) and noncancerous kidney cells (HEK-293T) to develop an efficient antican-cer medication.
Evaluation of Phytochemicals, Antioxidants, Trace Elements in Kigelia …
网页2019年8月20日 · Antioxidant potentials of K. africana fruit were investigated spectrophotometrically using hydroxyl ion scavenging (OH −) activity, metal ion chelating activity, anti-lipid peroxidation activity as well as total antioxidant capacity assays.
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