Laboratory Mice and Rats - labome.com
2023年12月25日 · A summary and overview of the mice and rats used in biomedical research, based on a survey of formal publications. C57BL/6 and BALB/c are the main mouse strains. Sprague-Dawley and Wistar are the main rat strains. The Jackson Laboratory, Charles River Laboratories, Taconic Biosciences, and Harlan Laboratories are the main suppliers.
The History of the Lab Rat Is Full of Scientific Triumphs and Ethical ...
2019年2月27日 · For decades, lab rats and mice have been used to make great scientific and medical advances, from cancer drugs and HIV antiretrovirals to the yearly flu vaccine. Lab mice—most often of...
Laboratory rat - Wikipedia
Laboratory rats or lab rats are strains of the rat subspecies Rattus norvegicus domestica (Domestic Norwegian rat) which are bred and kept for scientific research. While less commonly used for research than laboratory mice, rats have served as an important animal model for research in psychology and biomedical science. [1]
Mice and Rats as Laboratory Animals - MSD Veterinary Manual
Few infectious agents found in laboratory mice and rats today cause overt, clinical disease. Distinguishing between infection and disease is critical to interpreting the microbiologic status of laboratory animals.
Research-Relevant Conditions and Pathology of Laboratory Mice, Rats …
Rare in laboratory mice but common in wild rodents; causes follicular comedones (white nodules) on skin.
Mice vs Rats in Research: What’s the Difference? - Kent Scientific
2019年4月25日 · Rats show more compulsive and additive behavior, more impulsive behavior, and less self-restraint in waiting for a known reward. Mice are less impulsive and more able to control premature responses. Mice and rats have been shown to react very differently in their response to alcohol, nicotine, and MDMA.
With the advent of transgenic and other genetic engineering tech-nologies, the versatility and usefulness of the mouse as a model in biomedical research has soared. Revised to refect advances...
The Anatomy and Physiology of Laboratory Mouse
2021年7月24日 · Among the different types of vertebrate and invertebrate animals used in biomedical research, the laboratory mouse is the widely used vertebrate animal model. It remains the choice of model for many research hypotheses due to its small size, shorter life span, easy...
Rats on the rise | Lab Animal - Nature
2021年7月14日 · After a genetic revolution in the 80s, mice overtook rats as the laboratory animal of choice for many researchers. But in recent years, the gene editing capabilities that had lagged a little...
Distinct dynamics of social motivation drive differential social ...
2020年11月20日 · Mice and rats are widely used to explore mechanisms of mammalian social behavior in health and disease, raising the question whether they actually differ in their social behavior.