Levobupivacaine - Wikipedia
网页Levobupivacaine is a local anaesthetic drug indicated for minor and major surgical anaesthesia and pain management. It is a long-acting amide-type local anaesthetic that blocks nerve impulses by inhibiting sodium ion influx into the nerve cells. [1]
Levobupivacaine: Uses, Interactions, Mechanism of Action
网页Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZeneca under the trade name Chirocaine.
Levobupivacaine: Indications, Side Effects, Warnings - Drugs.com
网页2024年4月14日 · Easy-to-read patient leaflet for Levobupivacaine. Includes indications, proper use, special instructions, precautions, and possible side effects.
Clinical profile of levobupivacaine in regional anesthesia: A ...
网页Levobupivacaine, the pure S (−)-enantiomer of bupivacaine, has strongly emerged as a safer alternative for regional anesthesia than its racemic sibling, bupivacaine. Levobupivacaine has been found to be equally efficacious as bupivacaine, but with a superior pharmacokinetic profile.
左布比卡因 - 百度百科
网页产妇的复苏要比其他病人困难，心脏按压往往效果不佳，应尽快分娩或取出胎儿，以使复苏容易成功。. 左布比卡因（levobupivacaine）分子式为C18H29ClN2O，分子量为324.88900，密度为1.032 g/cm3，熔点为254ºC (dec.) (lit.)，沸点为423.4ºC at 760 mmHg，闪点为209.9ºC，库房通风 ...
Update on local anesthetics: focus on levobupivacaine - PMC
网页In recent years levobupivacaine, the pure S (−)-enantiomer of bupivacaine, emerged as a safer alternative for regional anesthesia than its racemic parent. It demonstrated less affinity and strength of depressant effects onto myocardial and central nervous vital centers in pharmacodynamic studies, and a superior pharmacokinetic profile.
Bupivacaine: Uses, Interactions, Mechanism of Action - DrugBank …
网页Levobupivacaine is a derivative, specifically an enantiomer, of bupivacaine. Systemic absorption of local anesthetics produces effects on the cardiovascular and central nervous systems. At blood concentrations achieved with therapeutic doses, changes in cardiac conduction, excitability, refractoriness, contractility, and peripheral vascular ...
Bupivacaine - StatPearls - NCBI Bookshelf
网页2023年8月17日 · This activity reviews the mechanism of action, adverse event profile, toxicity, dosing, pharmacodynamics, and monitoring of bupivacaine, pertinent for members of the interprofessional team for the treatment of patients when local anesthesia is warranted. Objectives: Outline the indications for the use of bupivacaine.
Levobupivacaine: a review of its pharmacology and use as a local ...
网页Levobupivacaine was generally as effective as bupivacaine for pain management during labour, and was effective for the management of postoperative pain, especially when combined with clonidine, morphine or fentanyl. The tolerability profiles of levobupivacaine and bupivacaine were very similar in clinical trials.
Clinical Pharmacokinetics and Pharmacodynamics of Levobupivacaine
网页Levobupivacaine is a long-acting amide local anaesthetic used in analgesia and anaesthesia. Like other local anaesthetic drugs, levobupivacaine exhibits effects on motor and sensory nerves by inhibiting the opening of voltage-gated sodium channels, and hence propagation of neuronal action potentials ….