Pathophysiology of diabetes: An overview - PubMed
2020年10月13日 · Diabetes mellitus is a chronic heterogeneous metabolic disorder with complex pathogenesis. It is characterized by elevated blood glucose levels or hyperglycemia, which results from abnormalities in either insulin secretion or insulin action or both.
Pathophysiology of Diabetes - an overview - ScienceDirect
Pathophysiology. The pathophysiology of diabetes is complex and involves several different hormones (i.e., insulin, glucagons, and growth). The interaction of these hormones with the liver and their involvement in renal function make the pathological mechanisms of this disease difficult to pinpoint and widely varied among patients.
Diabetes - StatPearls - NCBI Bookshelf - National Center for ...
2020年1月3日 · Describe the pathophysiology of diabetes mellitus. Outline the epidemiology and risk factors of diabetes mellitus. Review the treatment considerations and common complications of diabetes mellitus.
Type 2 diabetes mellitus in adults: pathogenesis, prevention and ...
2024年10月2日 · Diabetes is a heterogeneous syndrome characterized by defined hyperglycemia which is classified as type 1 diabetes (T1D), type 2 diabetes (T2D), specific types of diabetes and gestational...
Differentiation of Diabetes by Pathophysiology, Natural History…
2016年12月15日 · Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
Diabetes mellitus: From molecular mechanism to pathophysiology …
2023年9月1日 · It has a rapid prevalence globally, and there is a possibility of the statistic doubling in a few years. This review is aimed at evaluating the mechanism, pathophysiology, and pharmacology of diabetes mellitus.
Pathogenesis of Type 2 Diabetes Mellitus - Endotext - NCBI Bookshelf
2021年9月27日 · Numerous distinct pathophysiologic abnormalities have been associated with type 2 diabetes mellitus (T2DM). It is well established that decreased peripheral glucose uptake (mainly muscle) combined with augmented endogenous glucose production are characteristic features of insulin resistance.
Mechanisms underlying the pathophysiology of type 2 diabetes…
2022年2月1日 · The increasing burden of diabetes worldwide is evident and incontestable. In 2019, estimates indicated that 463 million people have diabetes, and by 2045 it is expected to affect over 700 million people around the world [1].
Pathophysiology of Type 2 Diabetes Mellitus - MDPI
2020年8月30日 · This review analyses the key aspects of T2DM, as well as the molecular mechanisms and pathways implicated in insulin metabolism and associations between T2DM and cardiovascular pathophysiology.
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology
2024年2月19日 · Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes1,2 and molecular mechanisms that are often specific to cell type3,4.