Pityriasis lichenoides et varioliformis acuta (PLEVA) pathology
Histology of PLEVA. PLEVA has sharply delimited, moderately dense, lymphocytic infiltrate involving the superficial vascular plexus, which extends in a wedge-shaped pattern to involve the lower dermis (figure 1). The superficial dermis shows a dense lichenoid infiltrate and impressive exocytosis of lymphocytes into the epidermis.
Pathology Outlines - Pityriasis lichenoides
Mar 14, 2022 · Pityriasis lichenoides et varioliformis acuta (PLEVA, acute form of the disease) is similar to PLC but with more pronounced histologic features: more interface damage, more inflammation, more erythrocytes in dermis and epidermis. Acute and chronic refer to the characteristics of the lesions.
Clinical, Dermatoscopic, and Histological Findings in a Diagnosis of ...
Pityriasis lichenoides et varioliformis acuta (PLEVA) is a rare cutaneous eruption of erythematous macules and papules distributed over the flexural surfaces and the trunk. Histopathologic analysis is useful in diagnosis, and dermoscopic findings ...
Pityriasis Lichenoides Et Varioliformis Acuta (PLEVA)
Jan 2, 2023 · Histopathology. A definitive diagnosis of PLEVA requires a thorough history, physical exam, and skin biopsy due to many diseases with similar clinical presentations. Many histopathologic findings for PLEVA confirm the diagnosis.
Pityriasis lichenoides (PLC, PLEVA): A Complete Overview
Histological features of PLEVA include: A wedge-shaped deep dermal and superficial lymphohistiocytic infiltrate; Parakeratotic scale and crust, with thinning of the granular layer; Interface dermatitis with basal cell necrosis and vacuolation; Epidermal spongiosis and necrosis in more developed lesions; Extravasated erythrocytes. In PLC there ...
Histopathologic Diagnosis of Pityriasis Lichenoides et Varioliformis ...
Pityriasis rosea, insect bites, and eczematous dermatitis accounted for the majority of the cases that histologically mimicked PLEVA. The constellation of histologic findings described in PLEVA (presence of intraepidermal lymphocytes and erythrocytes, dermal hemorrhage, and so-called lymphocytic vasculitis) is not specific and may be seen in a ...
Pityriasis lichenoides et varioliformis acuta (PLEVA)
Jul 23, 2024 · Pityriasis lichenoides et varioliformis acuta (PLEVA), otherwise known as Mucha-Habermann disease, is an uncommon cutaneous inflammatory disorder that most frequently affects young adults and children. PLEVA usually presents as an acute eruption of inflammatory papules and papulovesicles that rapidly develop hemorrhagic or necrotic crusts ...
Histopathologic diagnosis of pityriasis lichenoides et varioliformis ...
To assess the specificity of the histopathologic features in the diagnosis of pityriasis lichenoides et varioliformis acuta (PLEVA), we reviewed the clinical manifestations and courses of 42 patients for whom this diagnosis was suggested in the pathology report.
Pityriasis Lichenoides Et Varioliformis Acuta and Lymphomatoid ...
Aug 30, 2022 · Pityriasis lichenoides et varioliformis acuta (PLEVA) and lymphomatoid papulosis (LyP) are uncommon inflammatory skin disorders that occasionally share clinicopathological features. Differentiating between the two entities remains problematic, and a definitive diagnosis usually requires multi-step investigations, which is an enormous challenge ...
Pityriasis Lichenoides et Varioliformis Acuta: Case Report and …
Mar 23, 2012 · Histopathology showed necrotic keratinocytes with exocytosis of red blood cells and lymphocytes and a dermal perivascular and periadnexal inflammatory infiltrate, composed of CD8+/CD4–/CD30– T cells, indicating the clinical diagnosis of pityriasis lichenoides et varioliformis acuta.