Adenosine - Wikipedia
Adenosine is one of the four nucleoside building blocks of RNA (and its derivative deoxyadenosine is a building block of DNA), which are essential for all life on Earth. Its …
Landscape of adenosine-to-inosine RNA recoding across human …
2022年3月4日 · RNA editing by adenosine deaminases changes the information encoded in the mRNA from its genomic blueprint. Editing of protein-coding sequences can introduce novel, …
Programmed RNA editing with an evolved bacterial adenosine
2024年7月5日 · In this study, we developed bacterial deaminase-enabled recoding of RNA (DECOR), which employs an evolved Escherichia coli transfer RNA adenosine deaminase, …
RNA molecular recording with an engineered RNA deaminase
2023年10月19日 · An engineered RNA A-to-I deaminase (rABE) offers low sequence bias, high activity and low background for REMORA (RNA-encoded molecular recording in adenosines) …
Adenosine Deaminase Acting on RNA (ADAR) Enzymes: A …
2023年11月1日 · Adenosine deaminases acting on RNA (ADARs) are enzymes that convert adenosine to inosine in duplex RNA, a modification that exhibits a multitude of effects on RNA …
Adenosine-to-inosine RNA editing in neurological development …
2021年1月6日 · Adenosine-to-inosine (A-to-I) editing is one of the most prevalent post-transcriptional RNA modifications in metazoan. This reaction is catalysed by enzymes called …
Adenosine-to-inosine RNA editing and human disease
2013年11月29日 · A-to-I RNA editing is a post-transcriptional modification that converts adenosines to inosines in both coding and noncoding RNA transcripts. It is catalyzed by ADAR …
Adenosine-to-inosine RNA editing - PMC - National Center for ...
The most common type of RNA editing in vertebrates is the conversion of adenosine to inosine in double-stranded RNA which occurs in the higher eukaryotes. This editing is carried out by the …
Rewriting the transcriptome: adenosine-to-inosine RNA editing …
2017年10月30日 · One of the most prevalent forms of post-transcritpional RNA modification is the conversion of adenosine nucleosides to inosine (A-to-I), mediated by the ADAR family of …
Adenosine Deaminase Acting on RNA (ADAR) Enzymes: A …
2023年11月21日 · The adenosine deaminase acting on RNA (ADAR) enzymes that catalyze the conversion of adenosine to inosine in double-stranded (ds)RNA are evolutionarily conserved …