Reendothelialization - an overview | ScienceDirect Topics
网页Since accelerated reendothelialization of vascular stents and rapid restoration of endothelium integrity is the best strategy for preventing the recurrence of blood vessel occlusion (restenosis), the endothelialization of biomaterials has become an attractive approach including in vivo and in vitro endothelialization techniques.
Recent advances to accelerate re-endothelialization for vascular …
网页2017年9月28日 · Ways to improve re-endothelialization. According to the recent reports for accelerating re-endothelialization, three possible ways were used including changing the chemistry of the implant surface, changing the surface topography of the implant, and changing both of topography and chemistry of the implant surfaces.
Vascular inflammation and repair: implications for re ... - PubMed
网页Delayed re-endothelialization and impaired endothelial function are linked to stent thrombosis and adverse clinical outcomes after DES use. Compared with bare-metal stents, DES also differentially modulate mobilization, homing, and differentiation of vascular progenitor cells involved in re-endothelialization and neointimal proliferation.
Vascular Inflammation and Repair: Implications for Reendothelialization …
网页Understanding the common and differential molecular pathways that regulate reendothelialization vs. restenosis will provide a biological context for rational use of DES, and will enable development of new DES technologies that can inhibit neointimal proliferation and preserve or even promote endothelial repair.
Enhanced Reendothelialization and Thrombosis Prevention with …
网页2024年6月4日 · By enhancing reendothelialization and preventing thrombosis, CPEC offers advantages over conventional approaches, including the elimination of the need for anti-clogging drugs, which pave the way for improved therapeutic outcomes and management of atherosclerosis-related medical procedures.
Recent advances to accelerate re-endothelialization for vascular …
网页2017年9月28日 · Several molecules have been used to improve the cell-material interactions in order to enhance the adhesion and growth of ECs and consequently accelerate re-endothelialization, for example, heparin, fucoidan, chondroitin sulfate, hyaluronic acid, antioxidant compounds, and extracellular matrix (ECM) proteins including laminin, fibronectin, and c...
Paeonol Promotes Reendothelialization After Vascular Injury …
网页2023年5月24日 · This study provides evidence that Paeonol promotes reendothelialization following artery injury. Paeonol induces c-Myc expression, which is associated with VEGFR2, to accelerate reendothelialization and eventually suppress pathological vascular remodeling (Figure 7G).
The importance of reendothelialization after arterial injury
网页The increase in bone marrow release of endogenous progenitor cells or the enhancement of their homing in arterial denuded sites or in intravascular stent surface, are currently pursued to reduce atherosclerosis development/complication and intrastent restenosis, respectively.
Factors Affecting the Re-Endothelialization of Endothelial Progenitor ...
网页However, re-endothelialization is inevitably affected in vivo and in vitro by factors, which can be divided into two types, namely, promotion and inhibition, and act on different links of the vascular re-endothelialization. This article …
Resident Endothelial Cells Surrounding Damaged Arterial …
网页2010年6月17日 · After 6 hours, we continuously observed reendothelialization, identifying each EC, and found elongation, migration, and proliferation of resident ECs. Continual observation revealed that tips of most elongating ECs moved exactly side by side to the uncovered area, forming the clear edge of reendothelialization.
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