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Mescaline or mescalin (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic protoalkaloid of the substituted phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin. 展开
Mescaline induces a psychedelic state comparable to those produced by LSD and psilocybin, but with unique characteristics. Subjective effects may include altered thinking … 展开
Pharmacodynamics
Mechanism of action
In plants, mescaline may be the end-product of a pathway … 展开• Salvador Dalí experimented with mescaline believing it would enable him to use his subconscious to further his art potential
• Antonin Artaud 展开Peyote has been used for at least 5,700 years by Indigenous peoples of the Americas in Mexico. Europeans noted use of peyote in Native … 展开
Biosynthesis
Mescaline is biosynthesized from tyrosine which, in turn, is derived from phenylalanine by … 展开United States
In the United States, mescaline was made illegal in 1970 by the Comprehensive Drug Abuse Prevention and … 展开CC-BY-SA 许可证中的维基百科文本 What is synthetic mescaline? Is it not made from cactus in any way …
Synthetic mescaline is simply the primary active component of cacti, 3,4,5-trimethoxyphenethylamine, usually in a salt form such as hydrochloride or acetate. It's not …
Altered minds: mescaline’s complicated history - Nature
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Mescaline: A Global History of the First Psychedelic Mike Jay Yale University Press (2019) - Pharmacologists gave mescaline a fair trial. In the early and mid-twentieth century, it seemed m…
But this psychoactive alkaloid never found its clinical indication, as science writer Mike Jay explains in Mescaline, his anthropological and medical history. In the 1950s, the attention of biomedical researchers abruptly switched to a newly synthesized molecule with similar hallucino…
- 作者: Alison Abbott
- 发布日期: 2019年5月20日
- Publish Year: 2019
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What Happened to Mescaline? - Yale University Press
2019年8月6日 · Mescaline is one of the original psychedelics, but it has been overshadowed by LSD and its derivatives. Learn about its discovery, effects, research and cultural significance, as well as the difference between …
Mescaline - PsychonautWiki
2015年5月12日 · It is considered to be one of the best agents for psychedelic therapy due to its mellow, organic, yet complex character. Synthetic mescaline …
- Common: 200-400 mg
- Strong: 400-800 mg
- Light: 50-200 mg
- Threshold: 50 mg
Could Synthetic Mescaline Protect Declining Peyote …
2021年8月2日 · With populations of peyote rapidly dwindling due to loss of natural habitat and unsustainable harvesting practices, synthetically produced mescaline, along with cultivation of other mescaline rich cacti, offers a more ethical and …
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Mescaline: The forgotten psychedelic - ScienceDirect
2023年1月1日 · In the mid-50s, Herman Denber and Sydney Merlis gave intravenously 500 mg of synthetic mescaline sulphate to twenty-five patients diagnosed with schizophrenia to …
On the quest for mescaline | Nature Chemical Biology
2024年6月24日 · The mescaline biosynthetic pathway has been postulated for half a century; it entails hydroxylation and decarboxylation of l-tyrosine to dopamine through tyramine or l-3,4 …
Finding medical value in mescaline - Nature
2022年9月28日 · Mescaline also led the way in early Western medical experiments using psychedelic agents. It was first identified by scientists in 1897 and synthesized in 1919. Systematic clinical trials began...
The epidemiology of mescaline use: Pattern of use, motivations for ...
2021年5月5日 · Effective oral dosage of synthetic mescaline is in the 200–400 mg range, with three orders of magnitude greater than the equivalent dose of lysergic acid diethylamide (LSD) …
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