Tricyclic antidepressant poisoning - UpToDate
2024年7月19日 · Inhibition of presynaptic neurotransmitter reuptake (norepinephrine and serotonin) is the primary mechanism for the therapeutic effects of tricyclic antidepressants …
Tricyclic antidepressant overdose - Symptoms, diagnosis and treatment …
2024年4月5日 · Tricyclic antidepressant overdose should be suspected in patients with a history of depression, suicidality, and overdose presenting with a sudden deterioration in mental …
Tricyclic Antidepressant Toxicity - StatPearls - NCBI Bookshelf
2023年7月17日 · In adults, TCAs are also used in migraine headache prophylaxis, treatment of neuralgic pain, including the pain associated with Ciguatera poisoning, and obsessive …
Tricyclic Antidepressant Toxicity Treatment & Management - Medscape
An ECG/rhythm strip, if available, should be checked during the prehospital assessment of a patient with TCA overdose. A QRS duration longer than 100 msec is an indicator that the …
TCA toxicity • LITFL • Toxicology Library Toxicants
The mainstay of treatment for severe toxicity involves aggressive supportive care including the use of sodium bicarbonate for dysrhythmias and widening of the QRS alongside …
Tricyclic antidepressant overdose - Wikipedia
Tricyclic antidepressant overdose is poisoning caused by excessive medication of the tricyclic antidepressant (TCA) type. Symptoms may include elevated body temperature, blurred vision, …
Tricyclic antidepressant overdose: a review - Emergency …
Overdoses of tricyclic antidepressants are among the commonest causes of drug poisoning seen in accident and emergency departments. This review discusses the pharmacokinetics, clinical …
Tricyclic Antidepressant Overdose | TCA overdose | Geeky
2022年5月7日 · The key clinical features of TCA overdose include signs of anticholinergic toxicity and the result of sodium channel blockade. Severe effects include arrhythmia, cardiovascular …
Clinical Practice Guidelines : Tricyclic Antidepressant (TCA) Poisoning
Tricyclic antidepressants (TCA) are one of the common causes of a fatal drug overdose. They have a narrow therapeutic window so can be fatal at relatively lower doses and single tablet …
Tricyclic Antidepressant Toxicity - Medscape
Sodium bicarbonate, benzodiazepines, and norepinephrine are the drugs of choice for these complications. See Treatment and Medication. See also Tricyclic Antidepressant Toxicity in …