Cytologic patterns - eClinpath
Epithelioid macrophages are generally not phagocytic or vacuolated and mimic epithelial cells. The presence of multinucleated macrophages supports a granulomatous inflammatory response. Causes: Foreign body reactions, fungal infection, certain bacterial infections, such as Mycobacterium .
The vacuolization of macrophages induced by large amounts of …
We hypothesize that vacuoles are formed in large amounts during NP uptake by macrophages, which enhances the immune response and induces macrophages toward M1 polarization. These findings are potentially useful for disease treatment and understanding the immune response when NPs are used in vitro and in vivo .
Differential Diagnosis and Workup of Monocytosis: A …
Monocytes are characterized by expression of several cell surface receptors. This figure highlights some of those receptors and the key monocyte-associated functions such as macrophage-associated phagocytosis, dendritic cell-mediated antigen presentation, wound healing, interactions with coagulation cascade, and regulation of inflammatory ...
Barrier-tissue macrophages: functional adaptation to ... - Nature
Nov 7, 2017 · Macrophages are sessile mononuclear cells found in all tissues of the body, where they appear as large vacuolated cells with abundant cytoplasm containing lysosomal granules. Classically,...
The panorama of different faces of mesothelial cells - PMC
Vacuolated mesothelial cells with macrophage features (pleural fluid). Panorama of cytomorphologic features with central to slightly eccentric nuclei. [a–l, DQ-stained cytospin smears (a–l, 100X zoomed).] However, mesothelial cells with some features of macrophages may resemble malignant cells.
Cytoplasmic vacuolation, adaptation and cell death: A view on …
Sep 1, 1999 · Vacuoles developed within 2-3 h in the perinuclear region and occupied > 25% of the cytoplasmic volume. Similar data are found in Ohkuma and Poole (1981), following treatment of mouse peritoneal macrophages with chloroquine and other weakly basic substances.
Cytoplasmic vacuolization in cell death and survival - PMC
Cytoplasmic vacuolization (also called cytoplasmic vacuolation) is a well-known morphological phenomenon observed in mammalian cells after exposure to bacterial or viral pathogens as well as to various natural and artificial low-molecular-weight compounds.
Vacuolated macrophage with digested cells, bone marrow …
Nov 16, 2020 · Images A and B present vacuolated macrophages with digested cells inside phagosomes. Phagosomes fuses with lysosomes to complete the digestion process. Download Image
Morphometric Characterization of Rat and Human Alveolar Macrophage …
May 24, 2017 · “Foamy macrophage” is a term used by pathologists to describe an alveolar macrophage with a vacuolated cytoplasm when viewed by light microscopy [1, 2]. Currently, there are no universally accepted criteria to differentiate whether this vacuolated appearance constitutes an adaptive (non-adverse) or an adverse response.
Macrophages in cardiovascular diseases: molecular mechanisms …
May 31, 2024 · In this review, we systematically summarize the diverse phenotypic and functional plasticity of macrophages in regulatory mechanisms of cardiovascular diseases and unprecedented insights...