Oxymatrine - Wikipedia
Oxymatrine (matrine oxide, matrine N-oxide, matrine 1-oxide) is one of many quinolizidine alkaloid compounds extracted from the root of Sophora flavescens, a Chinese herb. It is very similar in structure to matrine, which has one less oxygen atom.
Oxymatrine: A current overview of its health benefits
2023年7月1日 · In this study, we offer a systematic review of natural occurrence, pharmacological potentials, possible mechanisms of action, pharmacokinetics, and bioavailability. Clinical research with OMT is needed to extensively elucidate its health potential benefits.
Oxymatrine - an overview | ScienceDirect Topics
Oxymatrine is a naturally occurring quinolizidine alkaloid derived from the roots of Sophora Flavescens Ait. Oxymatrine displays potent pharmacological properties, including being anti-fibrotic, anti-inflammatory, antimicrobial, and anti-allergic (He et al., 2015; Liu et al., 2014; Abd El-Rahman, Shehab, and Nashaat, 2017).
Oxymatrine: A current overview of its health benefits - PubMed
Growing studies revealed that OMT has a wide range of beneficial pharmacological values, consisting of anticancer, antidiabetic, antivirus, and antiinflammtion, as well as the protective activities to the brain, liver, heart, lung, vascular, gastrointestinal, bone, kidney, and skin organs.
Oxymatrine | C15H24N2O2 | CID 24864132 - PubChem
Oxymatrine | C15H24N2O2 | CID 24864132 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Oxymatrine: A current overview of its health benefits
2023年10月8日 · Oxymatrine (OMT) is an important quinoxaline alkaloid that has a wide range of pharmacological effects and has been shown to alleviate ulcerative colitis due to its profound anti-inflammatory...
Oxymatrine exerts organ- and tissue-protective effects by …
Oxymatrine is a quinazine alkaloid extracted from Sophora flavescens with various therapeutic effects such as organ- and tissue-protective, anti-inflammatory, anti-cancer, and anti-viral effects. In this review, we summarize the protective effects of oxymatrine on …
Oxymatrine exerts protective effects on osteoarthritis via …
Oxymatrine (OMT) is a natural compound with anti‐inflammatory and antitumour properties. We found that OMT exhibited a strong inhibitory effect on LPS‐induced chondrocyte inflammation and catabolism. To further support our results, fresh human cartilage explants were treated with LPS to establish an ex vivo degradation model, and the ...
Oxymatrine: A current overview of its health benefits
2023年7月1日 · In this study, we offer a systematic review of natural occurrence, pharmacological potentials, possible mechanisms of action, pharmacokinetics, and bioavailability. Clinical research with OMT is needed to extensively elucidate its health potential benefits.
Biopharmaceutical and Pharmacokinetic Activities of Oxymatrine ...
Abstract. Background: Oxymatrine is known as one of the most promising alkaloids from Sophora flavescens for its excellent pharmacological effects. Objective: The aim of this research is to assess the biopharmaceutical and pharmacokinetic activities of oxymatrine and clarify its mechanisms of absorption and metabolism.