Myo-inositol for insulin resistance, metabolic syndrome, polycystic ...
2022年3月2日 · Myo-inositol, also known as inositol (cyclohexanehexol), is a cyclic carbohydrate with six hydroxyl groups.1 For a long time, it was considered a B vitamin (vitamin B8). However, it is not considered an essential nutrient because it is formed from glucose. Each kidney makes around 2 g of myo-inositol per day, and the average dietary intake is 0.5–1.0 g/day.2 3 The …
Four pillars of heart failure: contemporary ... - Open Heart
2021年3月2日 · The past two decades have heralded dramatic improvements in outcomes for people living with heart failure with reduced ejection fraction (HFrEF). 1 The more widespread implementation of disease modifying pharmacological therapies,2 supported by landmark trials of renin-angiotensin system inhibitors3 and beta-blockers4 have improved longevity despite a …
Amlodipine in hypertension: a first-line agent with efficacy for ...
2016年9月28日 · Objectives Hypertension is well established as a major risk factor for cardiovascular disease. Although there is undeniable evidence to support the beneficial effects of antihypertensive therapy on morbidity and mortality, adequate blood pressure management still remains suboptimal. Research into the treatment of hypertension has produced a multitude of …
Vitamin K2—a neglected player in cardiovascular health: a …
Vitamin K2 serves an important role in cardiovascular health through regulation of calcium homeostasis. Its effects on the cardiovascular system are mediated through activation of the anti-calcific protein known as matrix Gla protein. In its inactive form, this protein is associated with various markers of cardiovascular disease including increased arterial stiffness, vascular and …
Homepage | Open Heart
Open Heart is dedicated to publishing high quality, peer reviewed medical research in all disciplines and therapeutic areas of cardiovascular medicine. Research is published across all study phases and designs, from protocols to phase I trials to meta-analyses, including small or specialist studies. Opinionated discussions on controversial ...
Echocardiographic diagnosis of right-to-left shunt using ...
2020年8月6日 · Introduction. Patent foramen ovale (PFO) is a common finding with a prevalence of about 25% in the general population.1 A strong association between PFO and ischaemic stroke has been reported.2 Pulmonary arteriovenous malformation (PAVM) is a rare disease in the general population and causes a permanent right-to-left shunt (RLS).3 The association of …
Transcatheter mitral valve repair: an overview of current and future ...
2021年4月28日 · The field of transcatheter mitral valve repair (TMVr) for mitral regurgitation (MR) is rapidly evolving. Besides the well-established transcatheter mitral edge-to-edge repair approach, there is also growing evidence for therapeutic strategies targeting the mitral annulus and mitral valve chordae. A patient-tailored approach, careful patient selection and an …
Cardiogenic shock: evolving definitions and future directions in ...
2019年5月8日 · Cardiogenic shock (CS) is a complex and highly morbid entity conceptualised as a vicious cycle of injury, cardiac and systemic decompensation, and further injury and decompensation. The pathophysiology of CS is incompletely understood but limited clinical trial experience suggests that early and robust support of the failing heart to allow for restoration of …
Magnesium for the prevention and treatment of cardiovascular …
2018年7月1日 · Magnesium is an essential mineral found in the body. It is naturally present in many foods and is also available as a dietary supplement. 1 It serves as a cofactor in more than 300 enzymatic reactions, such as those responsible for regulating blood pressure, glycaemic control and lipid peroxidation. It is therefore also critical to the cardiovascular system.1 The …
Classification of left ventricular size: diameter or volume with ...
2014年12月15日 · Background Left ventricular (LV) size is an important clinical variable, commonly assessed at echocardiography by measurement of the internal diameter in diastole (IDD). However, this has recognised limitations and volumetric measurement from apical views is considered superior, particularly with the use of echocardiographic contrast. We sought to …