组织纤维溶酶原激活物(t-PA) - 百度百科
网页(1)活性测定(t-pa∶a，发色底物法之一)： ①肝坏死常伴有纤溶活性的异常，由于消除功能障碍，故t-pa∶a往往增高。但同时由于pai的活性增强故t-pa的活性实际上是降低的。在dic和伴有血栓形成倾向的疾病往往有t-pa活性减低。冠心病心肌梗死患者pa活性减低。
Tissue-type plasminogen activator - Wikipedia
网页Tissue-type plasminogen activator (tPA) is a protein that breaks down blood clots and is used to treat ischemic stroke. Learn about its structure, function, medical uses, and risks of hemorrhage.
TPA（抗凝血药）_百度百科
网页TPA： 组织型纤溶酶原激活剂 又称 组织型纤溶酶原激活物 （tissue—type plasminogenactivator，t-PA）或 纤溶酶原激活因子 （tissue plasminogen activator），是体内纤溶系统的生理性激动剂，在人体纤溶和凝血的平衡调节中发挥着关键性的作用。. 属于糖蛋白,丝氨酸蛋白酶类 ...
How tPA (Tissue Plasminogen Activator) Works for Stroke
网页2023年10月6日 · tPA is a drug that dissolves blood clots in the brain and restores blood flow after a stroke. Learn how it works, who can get it, when to use it, and what are the side effects and risks.
Tissue Plasminogen Activator for Acute Ischemic Stroke (Alteplase ...
网页TPA (tissue plasminogen activator) is a clot-dissolving drug that can improve outcomes for acute ischemic stroke patients when given within three hours. Learn how NINDS played a major role in the development and approval of TPA, and how it works, when to use it, and what are the potential complications.
Tissue Plasminogen Activator - StatPearls - NCBI Bookshelf
网页2023年2月20日 · Tissue plasminogen activator (tPA) is classified as a serine protease (enzymes that cleave peptide bonds in proteins). It is thus one of the essential components of the dissolution of blood clots. Its primary function includes catalyzing the conversion of plasminogen to plasmin, the primary enzyme involved in dissolving blood clots. Recombinant ...
Intravenous Tissue Plasminogen Activator for Acute Ischemic Stroke
网页1998年1月1日 · Tissue plasminogen activator (t-PA) was demonstrated to be effective in the first 3 hours after acute ischemic stroke in a pivotal randomized clinical trial sponsored by the National Institutes of Neurological Disorders and Stroke (NINDS). 1 Questions regarding the safety and efficacy of t-PA in …
组织型纤溶酶原激活剂 - 百度百科
网页组织型纤溶酶原激活剂又称组织型纤溶酶原激活物（tissue—type plasminogenactivator，t-PA）或纤溶酶原激活因子（tissue plasminogen activator），是体内纤溶系统的生理性激动剂，在人体纤溶和凝血的平衡调节中发挥着关键性的作用。
Standard-Dose Intravenous Tissue-Type Plasminogen Activator for Stroke …
网页2014年7月10日 · Thrombolysis with intravenous tissue-type plasminogen activator (IV-tPA) remains the only proven effective intravenous treatment for acute ischemic stroke (AIS) within 4.5 hours of onset. 1, 2 The recommended dose of IV-tPA according to the National Institute of Neurological Disorders and Stroke (NINDS) trial was 0.9 mg/kg (maximum 90 mg). 1 Thi...
Generalized Efficacy of t-PA for Acute Stroke | Stroke
网页1997年11月1日 · There is evidence that intravenous thrombolysis with t-PA given within 3 hours of stroke onset improves long-term outcome. 1 Appropriately selected patients treated with t-PA had a 30% to 50% greater likelihood of nearly complete functional and neurological recovery relative to placebo-treated control subjects.